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BMSC Resource

The following sections contain scripts and data to reproduce results in the article "The Hippo-YAP/TAZ-TEAD axis promotes multipotency in bone marrow stromal cells".

Raw Data

All the raw data is deposited to the GEO database under accession number GSE234540

Scripts and Processed Data

BMSC Differentiation section

We collected Bone Marrow Stromal Cells (BMSCs) at four different time points - day 0, day 1, day 3, and day 7 - during the induction of three gold-standard lineages. The folder contains both the scripts and data necessary to reproduce the results.

BMSC Multipotency section

To address the observed discrepancy between heterogenous freshly isolated BMSCs and homogenous multipotent BMSCs, we collected BMSCs post-isolation at day 0, day 1, and day 3 to elucidate the derivation of multipotent BMSCs and identify critical regulators governing multipotency in BMSCs.

Python and R Environment

The environment.txt file lists detailed information about the package versions used in the analysis.