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VarDict calls many insertions in homopolymer regions #388

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Redmar-van-den-Berg opened this issue May 19, 2023 · 0 comments
Open

VarDict calls many insertions in homopolymer regions #388

Redmar-van-den-Berg opened this issue May 19, 2023 · 0 comments

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@Redmar-van-den-Berg
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I'm analysing RNAseq data from Leukemia samples using VarDict, and I'm finding a very high number of insertions in homopolymer regions, even if the homopolymer strechtes are quite short (5bp and up). This seems similar to the issue described here: #16

Is there any way to make VarDict less sensitive to these kinds of artefacts?
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@Redmar-van-den-Berg