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Attempt to identify tumor cells in those non-ETP samples without B cells (SCPCP000003) #811

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UTSouthwesternDSSR opened this issue Oct 15, 2024 · 0 comments
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If you are filing this issue based on a specific GitHub Discussion, please link to the relevant Discussion.

#630

Describe the goals of the changes to the analysis module.

The idea is to choose the best annotated sample with B cells (SPCL000703) and merge it with one of the samples without B cells, and correct the batch effect with Harmony, attempting to deduce the tumor/normal status of those cells from sample without B cells by the clustering pattern, if there is any.

What will your pull request contain?

scripts for merging/batch effect corrected object and showing the umap plots of object

Will you require additional software beyond what is already in the analysis module?

Harmony

Will you require different computational resources beyond what the analysis module already uses?

No response

If known, when do you expect to file the pull request?

~Today or tomorrow

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